National Projects
Epigenetic modeling/remodeling of cancer metastases and tumor immune contexture to improve efficacy of immunotherapy
Scientific Director: Prof. Daniela Massi
Funding agency: AIRC
Reference year: 2018
Start date: July 1, 2018
End date: December 31, 2026
Project type: competitive Research projects funded by other entities (Private)
The research investigates how the crosstalk between the tumor epigenome, tumor microenvironment (TME), and immune system contributes to metastasis and immunotherapy resistance, aiming to develop new therapeutic combinations based on epigenetic drugs + immunotherapy
Evaluation of pathogenic variants and study of gene polymorphisms through exomics in pediatric oncological and neuro-oncological patients with auxological, endocrinological, gynecological, and andrological disorders (ENDO-ONCO)
Scientific Director: Prof. Stefano Stagi
Funding agency: Bank of Italy
Reference year: 2019
Start date: March 1, 2026
End date: March 1, 2027
Project type: Research grant from other entities (Public)
The project investigates how genetic variants identified through exome sequencing (Whole Exome Sequencing) influence development, growth, and endocrine function in children and adolescents who have had oncological or neuro-oncological tumors
ReCo2: Re-Co-Very Through Co-Writing: The Implementation of a Collaborative Writing Approach in Mental Health Care
Scientific Director: Prof. Giovanni Stanghellini
Funding agency: MUR (PRIN Call)
Reference year: 2024
Start date: February 4, 2025
End date: February 4, 2027
Project type: Research revenues from competitive grants funded by MUR
The project investigates how collaborative writing (cowriting) can become a therapeutic and rehabilitative tool in mental health services, promoting recovery, empowerment, self-narrative, and active participation of people experiencing mental health challenges
Diabetes-associated systemic inflammation and Alzheimer disease progression from preclinical to clinical stage: from complex models to single cell level
Scientific Director: Prof. Domenico Edoardo Pellegrini-Giampietro
Funding agency: MUR (PRIN Call)
Reference year: 2024
Start date: February 4, 2025
End date: February 4, 2027
Project type: Research revenues from competitive grants funded by MUR
The aim of the research is to understand how diabetes and chronic systemic inflammation contribute to the onset of Alzheimer's disease, its progression from early preclinical stages to full clinical phases, and the cellular and molecular changes occurring in the brain and immune system
DOES BRAIN HISTAMINERGIC NEURONS’ ACTIVITY SHAPE RESILIENCE AND SUSCEPTIBILITY TO CHRONIC STRESS? A PRECLINICAL MULTIDISCIPLINARY STUDY
Scientific Director: Prof. Maria Beatrice Passani
Funding agency: MUR (PRIN Call)
Reference year: 2024
Start date: February 4, 2025
End date: February 4, 2027
Project type: Research revenues from competitive grants funded by MUR
The project utilizes a validated mouse model of repeated stress and advanced technologies to study how the brain histaminergic system influences resilience and susceptibility to stress. The results of the project can enhance our understanding of stress-related cognitive impairment and suggest innovative therapies
Schwann cell and hormone action in gender pain (WOMAN-PAIN)
Scientific Director: Prof. Francesco De Logu
Funding agency: MUR – via Italian Science Fund - Starting Grant
Reference year: 2025
Start date: June 1, 2025
End date: May 31, 2028
Project type: other national programs funded by MUR
The project aims to understand how Schwann cells and hormones modulate pain sensitivity differently between the sexes, helping to explain why women more frequently report chronic, more severe, and longer-lasting pain, while men display different pain thresholds and inflammatory responses.
Optimization of Oral Food Challenge for IgE-Mediated Food Allergy in Italian Pediatric Clinical Practice (OFC-OPTIPED)
Scientific Director: Dr. Mattia Giovannini
Funding agency: Dicogiovani ETS Foundation
Reference year: 2026
Start date: August 1, 2026
End date: July 31, 2028
Project type: competitive Research projects funded by other entities (Private)
The project aims to improve the safety, diagnostic accuracy, and efficiency of the Oral Food Challenge (OFC) — the clinical test considered the gold standard for diagnosing IgE-mediated food allergies in pediatric patients
Last update
31.07.2026